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Istradefylline 40 mg/working day enhanced peak ranges and AUC of CYP3A4 substrates in clinical trials. This influence was not noticed with istradefylline twenty mg/day. Think about dose reduction of delicate CYP3A4 substrates.Stiripentol is often a CYP3A4 inhibitor and inducer. Keep track of CYP3A4 substrates coadministered with stiripentol for amp